業績紹介

TOP > 研究・教育情報 > 業績紹介

2011年

Akita S, Akino K, Hirano A, Ohtsuru A, Yamashita S. Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury. Stem Cells Int. (in press)

2010年

Matsushima K, Isomoto H, Yamaguchi N, Inoue N, Machida H, Nakayama T, Hayashi T, Kunizaki M, Hidaka S, Nagayasu T, Nakashima M, Ujifuku K, Mitsutake N, Ohtsuru A, Yamashita S, Korpal M, Kang Y, Gregory PA, Goodall GJ, Kohno S, Nakao K. MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. J Transl Med. 2011 22;9(1):30.

Akita S, Akino K, Hirano A, Ohtsuru A, Yamashita S Mesenchymal stem cell therapy for cutaneous radiation syndrome. Health physics 98(6):858-862, 2010 Inoue N, Isomoto H, Matsuhima K, Hayashi T, Kunizaki M, Hidaka S, Machida H, Mitsutake N, Nanashima A, Takeshima F, Nakayama T, Ohtsuru A, Nakashima M, Nagayasu T, Yamashita S, Kazuhiko N, Kohno S Down-regulation of microRNA 10a expression in esophageal squamous cell carcinoma cells. Oncology Letters 1:527-531, 2010

Kumagai A, Ohtsuru A, Usa T, Mitsutake N, Yamashita S Molecular targeting therapy with external radiation for intractable and poor-prognosis thyroid carcinoma. Endocrine Journal 57(supple 2):S455-456, 2010

2009年

Takamura N, Ohtsuru A, Ozawa H, Yamashita S: Research activities and projects within a framework of international radiation health sciences research. pp81-89, Radiation Health Risk Sciences . Editors (Nakashima M, Takamura N, Tsukasaki K, Nagayama Y, Yamashita S) Springer 2009

2008年

Meng Z, Mitsutake N, Nakashima M, Starenki D, Matsuse M, Takakura S, Namba H, Saenko V, Umezawa K, Ohtsuru A, Yamashita S: DHMEQ, a novel NF-κB inhibitor, enhances anti-tumor activity of taxanes in anaplastic thyroid cancer cells. Endocrinology 149(11):5357-5365, 2008

Makino S , Mitsutake N, Nakashima M, Saenko VA, Ohtsuru A, Umezawa K, Tanaka K, Hirano A, Yamashita S: DHMEQ, a novel NF-kappaB inhibitor, suppresses growth and type I collagen accumulation in keloid fibroblasts. J Dermatol Sci 51(3):171-180, 2008

2007年

Kurobe M, Abe K, Kinoshita N, Anami M, Tokai H, Ryu Y, Wen CY, Kanematsu T, Hayashi T: Hyperplastic polyposis associated with two asynchronous colon cancers. World J Gastroenterol13(23):3255-8, 2007 Abe K, Kumagai K, Hayashi T, Kinoshita N, Shindo H, Uetani M, Ishida T: High-grade surface osteosarcoma of the hand. Skeletal Radiol 36(9):869-73, 2007

Morishita M, Ohtsuru A, Isomoto I, Yamashita S.: Categorization of Mammmographic Density for Breast Cancer: Clinical Significance. M. A. Hayat, Ed. Cancer Imaging, Elsevier, 305-312, 2007

improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy. Intern J Oncol31(2): 379-387, 2007

Izumo T, Ohtsuru A, Tokunaga Y, Namba H, Kaneda Y, Nagata I, Yamashita S: Epstein-Barr virus-based vector

Kumagai A, Namba H, Akanov Z, Saenko V. A, Meirmanov S, Ohtsuru A, Yano H, Maeda S, Anami M, Hayashi T, Ito M, Sagandikova S, Eleubaeva Z, Mussinov D, Espenbetova M, Yamashita S: Clinical Implications of Pre-Operative Rapid BRAF Analysis of Papillary Thyroid Cancer. Endocrine Journal54(3):399-405, 2007

N. Mitsutake, A. Iwao, K. Nagai, H. Namba, A. Ohtsuru, V. Saenko, S. Yamashita: Characterization of side population in thyroid cancer cell lines: Cancer stem-like cells are enriched partly but not exclusively. Endocrinology 148(4):1797-1803, 2007

S. Akita, K. Akino, A. Hirano, A. Ohtsuru, S. Yamashita: Reconstruction for local radiation injuries and proposed regeneration therapy for acute systemic radiation injuries. International Congress Series 1299:196-202, 2007 A. Kumagai, H. Namba, N. Mitsutake, A. Ohtsuru, M. Anami, T. Hayashi, M. Ito: Joint research project of genetic diagnosis of papillary thyroid cancer between Semipalatinsk Medical Academy and Nagasaki University. International Congress Series 1299:227-234, 2007

N. Ghotbi, M. Iwanaga, A. Ohtsuru, Y. Ogawa, S. Yamashita: Cancer Screening with Whole-body PET/CT for Healthy Asymptomatic People in Japan: Re-evaluation of its Test Validity and Radiation Exposure. Asian Pac J Cancer Prev 8(1):93-97, 2007Sato, N. Ashizawa, A. Ohtsuru, R. Imanishi, H. Kawano, S. Seto, S. Yamashita, I. Shimokawa, K. Yano: Fibrotic response to angiotensin II is blunted in the kidney, but not in the heart, in insulin-sensitive long-lived transgenic dwarf rats. Intern J Mol Medicine 19(1):23-27, 2007

2006年

N. Gotobi, A. Ohtsuru, M. Morishita, N. Norimatsu, H. Namba, H. Moriuchi, M. Uetani, S. Yamashita: Pediatric CT scan usage in Japan: results of a hospital survey. Radiation Medicine 24 (8): 560-567, 2006

I. Palona, N. Hiroyuki, N. Mitsutake, D. Starenki, A. Podtcheko, I. Sedliarou, A. Ohtsuru, V. Saenko, Y. Nagayama, K. Umezawa, S. Yamashita: BRAFV600E promotes invasiveness of thyroid cancer cells through NF-kB activation. Endocrinology 5699-5707, 2006

A. Kumagai, H. Namba, S. Takakura, E. Inamasu, VA. Saenko , A. Ohtsuru, S. Yamashita: No evidence of ARAF, CRAF and MET mutations in BRAF (T1799A) negative human papillary thyroid carcinoma. Endocr J 53(5):615- 620, 2006

A. Kumagai, H. Namba, N. Mitsutake, VA. Saenko, A. Ohtsuru, M. Ito, JY. Noh, K. Sugino, K. Ito, S. Yamashita: Childhood thyroid carcinoma with BRAFT1799A m

utation shows unique pathological features of poor differentiation. Oncol Rep 16(1):123-126, 2006

D. Bulgin, A. Podtcheko, S. Takakura, N. Mitsutake, H. Namba, V. Saenko, A. Ohtsuru, T. Rogounovitch, I. Palona, S. Yamashita: Selective pharmacologic inhibition of c-Jun NH2-terminal kinase radiosensitizes thyroid anaplastic cancer cell lines via induction of terminal growth arrest. Thyroid. 16(3):217-224, 2006

H. Isomoto, A. Ohtsuru, V. Braiden, M. Iwamatsu, F. Miki, Y. Kawashita, Y. Mizuta, Y. Kaneda, S.Kohno, S. Yamashita: Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer. Oncol Rep 15(3):629-635, 2006

A. Podtcheko, A. Ohtsuru, H. Namba, V. Saenko, D. Starenki, I. Palona, I. Sedliarou, T. Rogounovitch, S. Yamashita: Inhibition of ABL tyrosine kinase potentiates radiation-induced terminal growth arrest in anaplastic thyroid cancer cells. Radiat Res 165(1):35-42, 2006

Y. Kawashita, H. Fujioka, A. Ohtsuru, H. Kuroda, S. Eguchi, Y. Kaneda, S. Yamashita, T. Kanematsu: Total vascular exclusion safely facilitates liver speciic gene transfer by the HVJ (Sendai Virus)-liposome method in rats. J Surg Res 132(1):136-141, 2006

2005年

Y. Kawashita, H. Fujioka, A. Ohtsuru, Y. Kaneda, Y. Kamohara, Y. Kawazoe, S. Yamashita, T. Kanematsu: The efficacy and safety of gene transfer into the porcine liver in vivo by HVJ (Sendai virus) liposome. Transplantation 80(11):1623-9, 2005

M. Morishita, A. Ohtsuru, A. Kumagai, H. Namba, N. Sato, T. Hayashi, S. Yamashita: Vitamin D3 treatment for locally advanced thyroid cancer: a case report. Endocr J 52(5):613-6, 2005

Y. Kawashita, A. Ohtsuru, F. Miki, H. Kuroda, M. Morishita, Y. Kaneda, K. Hatsushiba, T. Kanematsu, S. Yamashita: Eradication of hepatocellular carcinoma xenografts by radiolabelled, lipiodol-inducible gene therapy. Gene Ther 12(22):1633-9, 2005

N. Ghtobi, M. Morishita, A. Ohtsuru, S. Yamashita: Evidence-based guidelines needed on the use of CT scanning in Japan. Japan Medical Association Journal 48 (9):451-457, 2005

M. Morishita, T. Hayashi, S. Maeda, H. Yano, I. Isomoto, K. Abe, M. Matsumoto, M. Anami, A. Ohtusru, S. Yamashita, T. Nagayasu, T. Kanematsu: Current and future strategy for breast cancer treatment at Nagasaki University Hospital. Acta Med Nagasaki 50(4):137-142, 2005

M. Morishita, A. Ohtsuru, H. Namba, S. Yamashita: The current situation and future scope of radiation emergency medical care network in Nagasaki. Acta Med Nagasaki 50(supple 1), 35-38, 2005

H. Isomoto, H. Ueno, VA. Saenko, MS. Mondal, Y. Nishi, N. Kawano, K. Ohnita, Y. Mizuta, A. Ohtsuru, S. Yamashita, M. Nakazato, S. Kohno. Impact of helicobacter pylori infection on gastric and plasma ghrelin dynamics in humans. Am J Gastroenterol 100(8): 1711-1720, 2005

K. Akino, S. Akita, T. Mizuguchi, I. Takumi, R. Yu, X. Wang, J. Rozga, A A. Demetriou, S. Melmed, A. Ohtsuru, S. Yamashita: A novel molecular marker of pituitary tumor transforming gene involves in rat liver regeneration. J Surg Res 129(1):142-146, 2005

A. Podtcheko, H. Namba, V. Saenko, A. Ohtsuru, D. Starenki, S. Meirmanov, I. Palona, T. Rogounovitch, S. Yamashita: Radiation-induced senescence-like terminal growth arrest in thyroid cells. Thyroid 15(4):306-313, 2005

M. Morishita, A. Ohtsuru, M. Nakashima, S. Yamashita: Unilateral multiple primary tumours in an atomic bomb survivor. Clinical Oncology 17(5):391-392, 2005

M. Morishita, A. Ohtsuru, T. Hayashi, I. Isomoto, N. Itoyanagi, S. Maeda, S. Honda, H. Yano, T. Uga, T. Nagayasu, T. Kanematsu, S. Yamashita: Clinical significance of categorization of mammographic density for breast cancer prognosis. Int J Oncol 26(5):1307-1312, 2005

K. Iwanaga, N. Takamura, Y. Abe, Y. Zhaojia, K. Shinzato, H. Hosoda, K. Kangawa, A. Ohtsuru, S. Kohono, S. Yamashita, K. Aoyagi: Plasma concentrations of adrenomedullin and ghrelin in hemodialysis patients with sustained and episodic hypotension. Endocr J 52(1):23-28, 2005

ページの先頭に戻る